Bioinformatics and Genomics platform - ICube (BiGEst-ICube) | ICube UMR 7357 | Engineering science, computer science and imaging laboratory

Your one-stop portal for all bioinformatics needs

The Bioinformatics and Genomics platform – BiGEst-ICube provides tailored bioinformatics services across a wide range of applications. Its activities span evolutionary, functional, and biomedical bioinformatics. The platform offers users scientific and technical expertise, as well as a comprehensive set of services, software tools, databases, and hardware resources.

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The platform

BiGEst-ICube brings together software, databases, hardware, and high-performance tools—all in one place.
Scientific and technical experts are available to help you make the most of these resources and guide you through their use.
Thanks to cutting-edge equipment, the platform also provides privileged access to powerful computing and data-storage solutions.
Data quality is at the heart of our expertise. We ensure rigorous data management throughout the entire data lifecycle.

Galerie

<strong>Réseau d'interaction des gènes liés à la multiciliation et structure 3D de protéine © BiGEst-ICube</strong>

<strong>Analyse d'alignement de séquences protéiques avec l'outil Ordalie © BiGEst-ICube</strong>

Expertise and resources

Scientific expertise

Analysis of relationships between sequence, structure, function, and evolution
Comparative genomics, from bacteria to metazoans
Study of rare genetic diseases

Technical expertise

Design of high-performance computing strategies
Machine learning
Optimization using evolutionary algorithms
Data stewarding: preparation, curation, and FAIRification of data

Core equiment

Computing and storage servers

Software and database resources

OrthoInspector: software and database for ortholog prediction
PipeAlign: software suite for generating multiple sequence alignments
Ordali: tool for visualizing and analyzing annotated multiple sequence alignments
GxDb: system for processing, analyzing, and visualizing transcriptomic data
EASEA: software for designing and deploying evolutionary algorithms on massively parallel architectures

Services

Omics analysis (transcriptomics, proteomics, metabolomics, lipidomics)
Data analysis: characterization, exploration, preparation, curation, FAIRification
Development of dedicated AI and machine learning models
Implementation of optimization methods

Keywords: bioinformatics, transcriptomics, metabolomics, proteomics, lipidomics, artificial intelligence, machine learning, optimization, multiple sequence alignment, data management

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