FMTS seminar : Multiparametric Imaging using Ultrafast Ultrasound

Jean PROVOST, CNRS research scientist at the Institut Langevin Paris will give a ED-MSII and FMTS seminar Wednesday, Mai 10th, 2017 at 2pm in the IRCAD Strasbourg (« L. HIRSCH » amphitheater).

He will present his activities on ultrafast ultrasonic imaging for:

• (1) brain and cardiac acoustoelectric imaging;
• (2) coupling with Positron Emission Tomography (PET).

Title: Multiparametric Imaging using Ultrafast Ultrasound

Abstract: Over the last fifteen years, the advent of 2-D Ultrafast Ultrasound Imaging has broken the conventional barriers of ultrasound imaging and has recently allowed for the extension of the applications of echography to new fields of study, such as the functional imaging of the brain, cardiac electrophysiology, and the quantitative imaging of tumors, to name a few, non-invasively and in real time. This presentation will explore the multiparametric, multiwave, and multimodal approaches used to develop these novel modalities.
In the first part of this presentation, we will describe how the mapping of various parameters of the recorded sound field such as the temporal, spatial, and spatiotemporal correlations of received signals can be leveraged to measure tissue and blood motion, which can then be used to map fiber orientation, the hemodynamic response of the brain, or electromechanical waves in the heart.
Two types of waves can also be combined to map tissue properties that cannot be retrieved by either one alone. Examples of such multiwave approaches include shear-wave imaging, optoacoustic imaging, and, most recently, acoustoelectric imaging. The second part of this presentation will describe the challenges and system design for Ultrafast Acoustoelectric Imaging, which is based on the combination of the electrocardiogram and ultrasonic plane waves.
Finally, we will describe a novel device capable of simultaneously performing Positron Emission Tomography (PET) and Ultrafast Ultrasound Imaging. PET is the most sensitive molecular imaging modality and as such can be used to characterize subtle biological pathways in vivo but cannot image tissue structure. UUI, on the other hand, can be performed at thousands of images per second with a 100-micron resolution to quantitatively map functions such as blood flow and tissue structure. When combined, UUI and PET become a powerful tool for the study of the interaction of metabolism and vasculature in tumors. Challenges then reside in extracting meaningful information out of complex 4-D maps of vasculature and metabolism.

Biography: Jean Provost completed his undergraduate and graduate studies at Ecole Polytechnique de Montreal, Canada, and Ecole Centrale Paris and Universite Paris-Sud, France, before obtaining his Ph.D. in biomedical engineering from Columbia University in New York in 2012. He is currently a CNRS Research Scientist at Institut Langevin in Paris, France. His main research interests include functional cardiac imaging, 3D ultrafast ultrasound imaging, and multiparametric imaging techniques.